Prof. Dr. Thilo Schlott

+49 661 9640-6460
+49 661 9640-6490
thilo.schlott(at)gw.hs-fulda.de

Human Biology and Statistics

Fulda University of Applied Sciences
Building 53, Room 147
Leipziger Straße 123
36037 Fulda

Consultation hours: By appointment by e-mail

CV

  • 1990 Studied biology at the Georg-August University of Göttingen, majoring in microbiology and molecular genetics, diploma.
  • 1994 Research assistant at the Institute of Hygiene at the University of Göttingen, doctorate (Dr. rer. nat.) on the pathogen of Lyme borreliosis
  • 2004 Scientific assistant in the Department of Cytopathology at the University of Göttingen: Head of molecular diagnostics, conducting tumour research and teaching, habilitation (Priv. Doz.) for the subject of molecular oncology at the Faculty of Medicine with a focus on hepatocellular carcinogenesis
  • Scientific assistant in the Department of Pathology at the University of Göttingen: Head of molecular diagnostics, conducting research and teaching
  • Scientific assistant at the Institute of Pathology, Klinikum Kassel GmbH: Head of molecular tumour diagnostics, supervision of cooperation projects with the pharmaceutical industry
  • Commissioned scientist at the German Archaeological Institute (DAI), Berlin, establishment of molecular archaeopathology
  • 2007 Public Health Studies at the University of Applied Sciences Fulda: Master of Science in Public Health
  • Managing Director of the HTCR Human Tissue & Cell Research Foundation, Regensburg/ Munich: structuring and standardisation of processes, control of tissue allocation, coordination with the European Network of Research Tissue Bank and other tissue banks
  • 2008 Professorship for Human Biology and Statistics at the University of Applied Sciences Fulda in the Faculty of Nursing and Health Care

Teaching and research activities abroad

  • 2000-2001 Department of Anatomical Pathology, Cape Town; PathCare Laboratories, Cape Town
  • 2002 Genome Sequence Center, British Columbia Cancer Research Center, Vancouver; TRIUMF, Canada's National Laboratory for Particle and Nuclear Physics, Vancouver; Dynacare Kasper Medical Laboratories, Edmonton
  • 2006 British Columbia Cancer Research Center, Vancouver

Honorary title

  • 2008 Appointed "Prof. (apl.)" at the Göttingen Faculty of Medicine by the President of the Georg-August University Göttingen

Teaching Areas

  • Medical microbiology and hygiene
  • Molecular Oncology
  • Human Biology
  • Evidence-based medicine EbM
  • Statistics

Areas of Research

  • Medical-historical analyses of diseases on the basis of hospital letters and administrative documents of the 19th and early 20th century

Publications

Selected publications

  • Schlott M, Schlott T (2018): Hahnemanns Patientenschaft: Die Krankengeschichte des Fernsdorfer Amtmanns und Rittergutsbesitzers Gottlob Friedrich Lüdicke und seiner Familie in Briefen. MedGG, Yearbook of the Institute for the History of Medicine of the Robert Bosch Stiftung (editor: Prof. Dr phil. Robert Jütte), 36, 153 - 178.
  • Weigand E, Schaper A, Schlott S (2018): Intoxications in correctional facilities. pg-papers, 01, Fulda.
  • Kreher S, Schlott M, Schlott T, Dölker S (2016): 'Protestant clergy in Hahnemann's patients - medical histories in letters'. MedGG, Yearbook of the Institute for the History of Medicine of the Robert Bosch Stiftung (Editor: Prof. Dr. phil. Robert Jütte), 34, 111 - 208.
  • Schlott T, Schlott M, Kreher S (2015): The "blood-coughing" Kleinpaschleben pastor Albert Wilhelm Gotthilf Nagel. Biographical-medical-historical reconstruction based on patient letters to Samuel Hahnemann. Mitteilungen des Vereins für Anhaltische Landeskunde, 23, 79 - 104.
  • Schlott T, Schlott M, Schliessmann B, Ungewickel B (2013): Health precautions against vectors (Subproject T4: "MüZe"), 351 - 364 in: "Interdisciplinary Research on Climate Change Mitigation and Adaptation" Regional Climate Adaptation: Challenges - Solutions - Obstacles - Implementations using the Example of Northern Hesse, Editor Roßnagel, Alexander, Kassel University Press.
  • Grebe M, Marr E, Seay C, Schlott T (2012): Chronic Lyme disease as a chameleon of medicine: burdens of a special patient group. Nursing Science, 06, 334 - 341
  • Schlott T, Gebhardt M (2012): Forestry work and health risk of ticks: a state-wide survey of Hessian forestry staff, AFZ-Der Wald, 10-11, 88 - 91.
  • Zahren J, Schlott T, Kreher S (2012): Patterns of risk perception and coping with Lyme disease - investigated by the example of a group discussion with farmers' wives in Northern Hesse. pg-papers, 02.
  • Gebhardt M, Schlott T (2011): Establishment of a population-based monitoring of potentially infectious vectors, project MüZe - a field report. Prevention and Health Promotion 6, 206 - 211
  • Schlott T, Eiffert H, Schmidt-Schulz T, Gebhardt M, Parzinger H, Schultz M (2008): Detection and analysis of tumour gene sequences amplified from bone material of a Scythian royal burial in Arzhan near Tuva, Siberia. Anticancer Res, 27, 4117 - 4119
  • Kunze E, Wendt M, Schlott T (2007):Methylation status of the genes 14-3-3 sigma, SYK, CAGE-1, Cav-1, and hDAB2IP in adenocarcinomas of the urinary bladder.Int J Mol Med, 20, 557 - 563
  • Kunze E, Von Bonin F, Werner C, Wendt M, Schlott T (2006): Transitional cell carcinomas and nonurothelial carcinomas of the urinary bladder differ in the promoter methylation status of the caveolin-1, hDAB2IP and p53 genes, but not in the global methylation of Alu elements.Int J Oncol, 17, 3 -13
  • Kunze E, Wendt M, Schlott T (2006):Promoter hypermethylation of the 14-3-3 sigma, SYK and CAGE-1 genes is related to the various phenotypes of urinary bladder carcinomas and associated with progression of transitional cell carcinomas. Int J Mol Med, 18, 547 - 57
  • Schlott T, Eiffert H, Bohne W, Landgrebe J, Brunner E, Spielbauer B, Knight B (2005):Chlamydia trachomatis modulates expression of tumor suppressor gene caveolin-1 and oncogene C- myc in the transformation zone of non-neoplastic cervical tissue. Gynecol Oncol, 98, 409 - 419
  • Thasler WE*, Schlott T*, Thelen P, Hellerbrand C, Bataille F, Lichtenhauer M, Schlitt HJ, Jauch KW, Weiss T (2005):Expression of augmenter of liver regeneration (ALR) in human liver cirrhosis and carcinoma (*shared first authorship). Histopathology, 47, 57 - 66
  • Schlott T, Quentin T, Korabiowska M, Budd B, Kunze E (2004): Alteration of the MDM2-p73-P14ARF pathway related to tumour progression during urinary bladder carcinogenesis. Int J Mol Med, 14, 825 - 836
  • Schlott T, Taubert H, Fayyazi A, Schweyer S, Bartel F, Korabiowska M, Brinck U (2004):Analysis of central regulatory pathways in p53-deficient primary cultures of malignant fibrous histiocytoma exposed to ifosfamide. Anticancer Res, 24, 3819 - 3829
  • Soruri A, Fayyazi A, Gangl S, Griesinger C, Albrecht CA, Schlott T (2004): In vitro generation of cytolytic T cells against human melanoma cells overexpressing HDM2. Anticancer Res, 24, 2141 - 2151.
  • Nagel H, Laskawi R, Eiffert H, Schlott T (2003):Analysis of the tumor suppressor genes FHITand WT-1 and the tumor rejection genes BAGE, GAGE-1/-2, HAGE, MAGE-1, MAGE-3 in benign and malignant tumors of the salivary gland. J Clin Pathol, 56, 226 - 231
  • Stuerzenhofecker B*, Schlott T*, Quentin T, Jung C, Truemper (2003): Abundant expression of spliced HDM2 in Hodgkin lymphoma cells does not interfere with P14ARF and p53 binding. (*shared first authorship) Leukemia Lymphoma, 44, 1587 - 1596
  • Schlott T, Scharf JG, Gorzel C, Middel P, Spring H (2002): Cirrhotic livers reveal genetic changes in the MDM2-P14ARF system of cell cycle regulators. Br J Cancer 86, 1290 - 1296
  • Schlott T, Thasler WE, Gorzel C, Pahernik S, Brinck U, Eiffert H, Droese M (2002): Detection of MDM2 alterations in cultured human hepatocytes treated with 17b-estradiol or 17a-ethinylestradiol. Anticancer Res 22, 1545 - 1552
  • Schlott T, Nagel H, Laskawi R, Eiffert H, Droese M (2001):Genetic analysis of the human oncoprotein MDM2 in benign and malignant tumours of the salivary gland.Pathobiology 69, 67 - 76
  • Schlott T, Scharf JG, Soruri A, Fayyazi A, Griesinger C, Albrecht C, Eiffert H, Droese M (2001): Fragments of human oncoprotein MDM2 reveal variable distribution within and on cultivated human hepatoma cells. Biochem Biophys Res Com 283, 956 - 963
  • Schlott T, Middel P, Laskawi R, Brinck U, Ruschenburg I, Droese M (2000):Relationship between GAGE-1/-2 expression, EBV infectionand interferon-g expression in undifferentiated carcinoma of nasopharyngeal type. Anticancer Res 20, 1727 - 1732
  • Schlott T, Ahrens K, Ruschenburg I, Reimer S, Hartmann H, Droese M (1999): Different gene expression of MDM2, GAGE-1,-2 and FHIT in hepatocellular carcinoma and focal nodular hyperplasia. Br J Cancer 80, 73 - 78
  • Schlott T, Ruda G, Hoppert M, Nagel H, Reimer S, Schumacher-Luetge IK, Droese M (1998):The in situ polymerase chain reaction for detection of Chlamydia trachomatis. J Histochem Cytochem 46, 1017 - 1023
  • Schlott T, Nagel H, Ruschenburg I, Reimer S, Droese M (1997):Reverse transcriptase polymerase chain reaction for detecting Ewing's sarcoma in archival fine needle aspiration biopsies. Acta Cytol 41, 795 - 801
  • Schlott T, Reimer S, Jahns A, Ohlenbusch A, Ruschenburg I, Nagel H, Droese M (1997): Point mutations and nucleotide insertions in the MDM2 zinc finger structure of human tumours. J Pathol 182, 54 - 61

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